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Marchiafava-Bignami disease: use of contrast media in CT and MRI.

Abstract
We report two cases of Marchiafava-Bignami disease studied by CT and MRI. Both patients displayed persistent confusion and a disconnection syndrome but had a favourable outcome. In both cases, CT with intravenous contrast medium revealed enhancement of the corpus callosum in the early stage. MRI showed gadolinium uptake in both the genu and splenium of the corpus callosum in one case, 8 days after the onset. Three weeks after admission, cystic lesions appeared in the corpus callosum on MRI T1-weighted sagittal images in both cases. Contrast medium uptake may be useful in the diagnosis of Marchiafava-Bignami disease.
AuthorsD Caparros-Lefebvre, J P Pruvo, E Josien, B Pertuzon, J Clarisse, H Petit
JournalNeuroradiology (Neuroradiology) Vol. 36 Issue 7 Pg. 509-11 (Oct 1994) ISSN: 0028-3940 [Print] Germany
PMID7845572 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Contrast Media
Topics
  • Adult
  • Alcoholism (complications, diagnostic imaging, pathology)
  • Contrast Media
  • Corpus Callosum (diagnostic imaging, pathology)
  • Demyelinating Diseases (diagnostic imaging, etiology, pathology)
  • Humans
  • Magnetic Resonance Imaging (methods)
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed (methods)

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