Embryonal rhabdomyosarcoma of the floor of the mouth. A case report.

Abstract

Rhabdomyosarcoma is a neoplasm composed of striated muscle. One of the most common types of soft tissue mesenchymal tumors in infants, children, and adolescents, rhabdomyosarcoma was considered an almost uniformly fatal cancer as recently as 30 years ago. Presently a multimodal approach consisting of surgery, radiation, and chemotherapy has significantly improved the outlook for the patient with rhabdomyosarcoma. This article presents a case of intraoral rhabdomyosarcoma that was initially poorly controlled because of a lack of patient compliance. After proper treatment, the cancer went into remission. The patient remained cancer-free for 7 years, albeit with significant morbidity. This case demonstrates the significantly improved prognosis achieved with multimodal therapy.

• Authors: S Meehan, V Davis, J S Brahim
• Journal: Oral surgery, oral medicine, and oral pathology (Oral Surg Oral Med Oral Pathol) Vol. 78 Issue 5 Pg. 603-6 (Nov 1994) ISSN: 0030-4220 [Print] United States
• PMID: 7838467 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dactinomycin
• Vincristine
• Cyclophosphamide

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Combined Modality Therapy
• Cyclophosphamide (administration & dosage)
• Dactinomycin (administration & dosage)
• Female
• Humans
• Mouth Floor (pathology)
• Mouth Neoplasms (pathology, therapy)
• Patient Compliance
• Prognosis
• Remission Induction
• Rhabdomyosarcoma, Embryonal (pathology, therapy)
• Vincristine (administration & dosage)