Abstract | BACKGROUND: METHODS: We conducted a masked, prospective trial involving 3117 infants born over a period of 30 months in a hospital in Kenya. Shortly after birth each infant received a 2.5 percent solution of povidone-iodine (n = 1076), a 1 percent solution of silver nitrate (n = 929), or 0.5 percent erythromycin ointment (n = 1112) in both eyes. Randomization was achieved by rotating the three medications after each was used for a week. RESULTS: CONCLUSIONS:
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Authors | S J Isenberg, L Apt, M Wood |
Journal | The New England journal of medicine
(N Engl J Med)
Vol. 332
Issue 9
Pg. 562-6
(Mar 02 1995)
ISSN: 0028-4793 [Print] United States |
PMID | 7838190
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Ophthalmic Solutions
- Erythromycin
- Povidone-Iodine
- Silver Nitrate
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Topics |
- Erythromycin
(administration & dosage, therapeutic use)
- Female
- Humans
- Infant, Newborn
- Logistic Models
- Male
- Ophthalmia Neonatorum
(prevention & control)
- Ophthalmic Solutions
- Povidone-Iodine
(administration & dosage, therapeutic use)
- Silver Nitrate
(administration & dosage, therapeutic use)
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