[Erythrokeratolysis hiemalis. Erythematosquamous genetic dermatosis with seasonal manifestation].

Abstract

Erythrokeratolysis hiemalis, keratolytic winter erythema or Oudtshoorn skin has been reported from the South African district of Oudtshoorn as a dominantly inherited dermatosis beginning in early childhood, in some cases with circinar scaling erythemas. Seasonal manifestation in winter-time and a characteristic multi-form histology distinguish this dermatosis from other childhood scaling erythemas. We present clinical, histological and preliminary immunohistological data of a 4-year-old girl with the attributes of erythrokeratolysis hiemalis. No ancestors from the endemic region were traced. The lack of further cases in the family is interpreted as indicative of a spontaneous dominant new mutation.

• Authors: D Krahl, A Sigwart, W Hartschuh, I Anton-Lamprecht, D Petzoldt
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 45 Issue 11 Pg. 776-9 (Nov 1994) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Erythrokeratolysis hiemalis. Erythematosquamöse Genodermatose mit saisonaler Manifestation.
• PMID: 7822203 (Publication Type: Case Reports, Journal Article)

Chemical References

• Leukocyte Common Antigens

Topics

• Child, Preschool
• Dermatitis, Exfoliative (diagnosis, genetics, pathology)
• Female
• Genes, Dominant
• Humans
• Immunohistochemistry
• Leukocyte Common Antigens (genetics)
• Microscopy, Electron
• Periodicity
• Seasons
• Skin (pathology)