Contact allergy to 2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol, components of a phenolic resin used in marking pens.

Abstract

2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol were identified as contact allergens in a phenolic resin used as a tackifier in the ink of a marking pen, which, after being used directly on the skin, caused an acute contact dermatitis on the hand of a 13-year-old boy. The patient also reacted to 4-tert-butylphenol-formaldehyde resin (BPF resin) 1% pet. included in the European standard series.

• Authors: H Hagdrup, H Egsgaard, L Carlsen, K E Andersen
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 31 Issue 3 Pg. 154-6 (Sep 1994) ISSN: 0105-1873 [Print] England
• PMID: 7821007 (Publication Type: Case Reports, Journal Article)

Chemical References

• Allergens
• Butylated Hydroxytoluene
• 2,6-bis(hydroxymethyl)-4-tert-butylphenol
• 2-hydroxy-5-tert-butylbenzyl alcohol

Topics

• Acute Disease
• Adolescent
• Allergens
• Butylated Hydroxytoluene (adverse effects, analogs & derivatives, metabolism)
• Dermatitis, Allergic Contact (etiology)
• Hand Dermatoses (etiology)
• Humans
• Ink
• Male