[Dietary effects of PUFA omega-3 on lipid peroxidation and antioxidant system in patients with IHD, hyperlipoproteinemia and hypertension].

Abstract

Dietary effects of polyunsaturated fatty acids (PUFA) omega-3 on lipid peroxidation (LPO) and antioxidant system were studied in 73 patients with ischemic heart disease, hyperlipoproteinemia (HLPE) type IIa, IIb, IV and essential hypertension. Eiconol-enriched antiatherosclerotic diet has more potent hypolipidemic, hypotensive and thrombolytic action in association with inhibition of LPO, enhances SOD activity, keeps red cell catalase within normal. Vitamin E concentrations were not changed. It is suggested that eiconol addition to antiatherosclerotic diet causes no LPO induction and is pathognomonic for HLPE, hypertension and IHD patients.

• Authors: A V Pogozheva, E A Martynova, M A Samsonov, N I Egorova, E A Ksenofontova, E G Gorozhanskaia
• Journal: Voprosy pitaniia (Vopr Pitan) Issue 4 Pg. 40-2 ( 1994) ISSN: 0042-8833 [Print] Russia (Federation)
• Vernacular Title: Vliianie diety s PNZK omega-3 na pokazateli POL i antioksidantnoĭ sistemy u bol'nykh IBS, giperlipoproteidemieĭ i gipertonicheskoĭ bolezn'iu.
• PMID: 7817530 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Antioxidants
• Dietary Fats, Unsaturated
• Fatty Acids, Omega-3
• Vitamin E
• Catalase

Topics

• Adult
• Aged
• Antioxidants
• Catalase (blood)
• Coronary Disease (diet therapy)
• Dietary Fats, Unsaturated (administration & dosage)
• Erythrocytes (enzymology)
• Evaluation Studies as Topic
• Fatty Acids, Omega-3 (administration & dosage)
• Female
• Humans
• Hyperlipoproteinemias (diet therapy)
• Hypertension (diet therapy)
• Lipid Peroxidation
• Male
• Middle Aged
• Vitamin E (blood)