Abstract | INTRODUCTION: METHODS: RESULTS: The two randomized groups were similar in relation to baseline clinical and hemodynamic characteristics. Nausea was documented in 103 patients (16.1%) with similar incidence in the two groups (control group: 16.8%, metoclopramide group: 15.5%; p = NS). Nausea duration was also similar (56 +/- 63 s vs 52 +/- 63 s; p = NS). When patients with and without nausea were compared, the following variables showed a significant difference between the two groups: male gender (86% vs 76%; p < 0.05), age (53 +/- 10 yrs vs 56 +/- 9 yrs; p < 0.05) and body surface area (1.84 +/- 0.2 m2 vs 1.78 +/- 0.1 m2; p < 0.01). Stepwise multiple regression analysis identified low age (p = 0.02) and male gender (p = 0.06) as independent predictors of nausea. The incidence of nausea was 24% in males < or = 45 yrs vs 9% in females > 45 yrs (p < 0.05). CONCLUSIONS:
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Authors | J A Gómez-Hospital, A Cequier, J Sala, J Mauri, C Catarino, M Sabaté, J E Barthe, L Valerio, F Jara, E Esplugas |
Journal | Revista espanola de cardiologia
(Rev Esp Cardiol)
Vol. 47
Issue 11
Pg. 729-34
(Nov 1994)
ISSN: 0300-8932 [Print] Spain |
Vernacular Title | Mecanismo de producción de las náuseas duŕante la ventriculografía realizada con ioxaglato: implicaciones de un estudio randomizado. |
PMID | 7800902
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Metoclopramide
- Diazepam
- Ioxaglic Acid
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Topics |
- Administration, Oral
- Diazepam
(therapeutic use)
- Drug Therapy, Combination
- Electrocardiography
(drug effects)
- Female
- Gated Blood-Pool Imaging
- Hemodynamics
(drug effects)
- Humans
- Ioxaglic Acid
(adverse effects)
- Male
- Metoclopramide
(therapeutic use)
- Middle Aged
- Nausea
(chemically induced, prevention & control)
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