Abstract | OBJECTIVE: METHODS: Forty adult mongrel dogs were equally divided into four groups: group I (PO-control) received sham ligation of common bile duct (CBDL) and was fed dog chow and water ad libitum; group II (PO-CBDL) underwent CBDL and was fed dog chow; group III (TPN-control) received sham CBDL and TPN; and group IV (TPN-CBDL) underwent CBDL and received TPN. Blood chemistries, plasma amino acids and liver histologies were studied before (Day 1) and at the end (Day 14) of the experiment. RESULTS: CONCLUSION: In the presence of obstructive jaundice, TPN does not significantly affect carbohydrate or lipid metabolism. However, a derangement in protein metabolism with the standard TPN solution in current use suggests that either a modification of amino acid composition or an increase in total energy to protein energy ratio in TPN solution may be necessary to obviate such a consequence.
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Authors | J H Chuang, C S Shieh, N K Chang, W J Chen, S K Lo |
Journal | Journal of the American College of Nutrition
(J Am Coll Nutr)
Vol. 14
Issue 2
Pg. 197-201
(Apr 1995)
ISSN: 0731-5724 [Print] United States |
PMID | 7790696
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Amino Acids
- Amino Acids, Branched-Chain
- Triglycerides
- Tyrosine
- Phenylalanine
- Ammonia
- Cholesterol
- Alkaline Phosphatase
- Bilirubin
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Topics |
- Alkaline Phosphatase
(blood)
- Amino Acids
(blood)
- Amino Acids, Branched-Chain
(blood)
- Ammonia
(blood)
- Animals
- Bilirubin
(blood)
- Cholestasis
(metabolism, therapy)
- Cholesterol
(blood)
- Common Bile Duct
- Dogs
- Female
- Ligation
- Male
- Parenteral Nutrition, Total
- Phenylalanine
(blood)
- Triglycerides
(blood)
- Tyrosine
(blood)
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