Abstract | PURPOSE: METHODS AND MATERIALS: RESULTS: All 24 malignant lesions were detectable in the pretreatment study. In all but one case, the tumor SUV decreased after radiotherapy. The median SUV of the tumor site was smaller (1.9, range, 1.3-3.1, n = 7) in cases with histologically verified complete response than in cases with persistent cancer (median 4.1, range, 2.8-7.6, n = 12, p = 0.0008). A complete histological response was verified in none of the 9 cases with a postirradiation SUV larger than the median (3.1), whereas 7 of the 10 cases with a SUV of 3.1 or smaller had complete response (p = 0.003). The preirradiation uptake of [11C] methionine in tumors did not have significant association with histological response (p = 0.45). The PET findings correlated well with follow-up data in five cases with unoperated tumor sites. The [11C] methionine uptake of the submandibular salivary glands decreased after radiotherapy (p = 0.04). CONCLUSION:
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Authors | P Lindholm, S Leskinen-Kallio, R Grénman, P Lehikoinen, K Någren, M Teräs, U Ruotsalainen, H Joensuu |
Journal | International journal of radiation oncology, biology, physics
(Int J Radiat Oncol Biol Phys)
Vol. 32
Issue 3
Pg. 787-94
(Jun 15 1995)
ISSN: 0360-3016 [Print] United States |
PMID | 7790265
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Carbon Radioisotopes
- Methionine
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Carbon Radioisotopes
- Carcinoma, Adenoid Cystic
(diagnostic imaging, radiotherapy)
- Carcinoma, Squamous Cell
(diagnostic imaging, radiotherapy)
- Female
- Head and Neck Neoplasms
(diagnostic imaging, radiotherapy)
- Humans
- Male
- Methionine
- Middle Aged
- Plasmacytoma
(diagnostic imaging, radiotherapy)
- Tomography, Emission-Computed
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