I-123 MIBG imaging of metastatic carcinoid tumor from the rectum.

Abstract

I-131 MIBG, a specific radiopharmaceutical agent for scintigraphic imaging and treatment of pheochromocytoma and neuroblastoma may be useful for detection of apudomas. Scintigraphy with I-123 radiolabeled MIBG was performed in a patient with metastatic carcinoid tumor from the rectum. I-123 MIBG scintigraphic findings showed multiple areas of abnormal tumor uptake of hepatic and bone metastases from the rectal carcinoid. Bone scintigraphy demonstrated multiple metastatic lesions. Computed tomography revealed multiple solid tumors of the liver. This report describes accumulation of I-123 MIBG in the liver and bone metastases from the rectal carcinoid. Radioiodine MIBG scintigraphy may be useful for detecting metastatic lesions, for evaluating postoperative recurrence, and also for the treatment of the carcinoid tumor.

• Authors: N Watanabe, H Seto, M Ishiki, M Shimizu, M Kageyama, Y W Wu, T Nagayoshi, Y Kamisaki, M Kakishita
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 20 Issue 4 Pg. 357-60 (Apr 1995) ISSN: 0363-9762 [Print] United States
• PMID: 7788995 (Publication Type: Case Reports, Journal Article)

Chemical References

• Contrast Media
• Iodine Radioisotopes
• Iodobenzenes
• 3-Iodobenzylguanidine

Topics

• 3-Iodobenzylguanidine
• Aged
• Bone Neoplasms (diagnostic imaging, secondary)
• Bone and Bones (diagnostic imaging)
• Carcinoid Tumor (diagnostic imaging, secondary)
• Contrast Media
• Female
• Humans
• Iodine Radioisotopes
• Iodobenzenes
• Liver (diagnostic imaging)
• Liver Neoplasms (diagnostic imaging, secondary)
• Radiography
• Radionuclide Imaging
• Rectal Neoplasms (pathology)