Abstract |
An 18-year-old man was treated from birth with chronic high dose pyridoxine ( vitamin B6) up to 2000 mg per day for pyridoxine-dependent seizures. Within two years of onset of treatment, he developed a sensory neuropathy which did not progress over the following 16 years. Electrophysiological studies were consistent with a pure sensory neuronopathy expressed as centripetal degeneration of processes of the dorsal root ganglion cells.
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Authors | R S McLachlan, W F Brown |
Journal | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
(Can J Neurol Sci)
Vol. 22
Issue 1
Pg. 50-1
(Feb 1995)
ISSN: 0317-1671 [Print] England |
PMID | 7750075
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Action Potentials
- Adolescent
- Electrophysiology
- Epilepsy
(drug therapy)
- Ganglia, Spinal
- Humans
- Iatrogenic Disease
- Male
- Pyridoxine
(adverse effects, pharmacology)
- Seizures
- Sensation Disorders
- Tibia
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