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[Clinical studies on SY5555 in pediatrics].

Abstract
SY5555 in dry syrup (powder which is dissolved before use) or tablet form was given orally to 21 children with acute bacterial infections including 4 with acute pharyngitis, 5 with acute tonsillitis, 7 with acute bronchitis, 2 with acute gastroenteritis, 1 each with scarlet fever, acute lymphadenitis and urinary tract infection. Good to excellent clinical responses were obtained in all of the 21 patients and 8 of 11 strains found as causative organisms in these cases were eradicated and 3 strains were decreased. Loose stools were observed in 3 cases and eosinophilia was observed in 1 case. From the above clinical results, it appears that SY5555 is a useful antibiotic for the treatment of pediatric patients with various bacterial infections.
AuthorsT Sekiguchi, T Okamoto
JournalThe Japanese journal of antibiotics (Jpn J Antibiot) Vol. 48 Issue 2 Pg. 220-8 (Feb 1995) ISSN: 0368-2781 [Print] Japan
PMID7745812 (Publication Type: Case Reports, Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Carbapenems
  • Powders
  • Tablets
  • SUN 5555
Topics
  • Administration, Oral
  • Bacteria (drug effects, isolation & purification)
  • Bacterial Infections (drug therapy, microbiology)
  • Carbapenems (administration & dosage, pharmacology)
  • Child
  • Child, Preschool
  • Drug Resistance, Microbial
  • Female
  • Humans
  • Infant
  • Male
  • Powders
  • Tablets

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