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[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].

Abstract
The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy. Twelve of them had infantile spasms, four Lennox-Gastaut syndrome. The treatment produced good results in 75% of the patients. Encorat mono- or polychemotherapy is able to discontinue or decrease the frequency of the epileptic fits, improve the patients' condition in resistant early childhood epilepsy.
AuthorsL O Badalian, P A Temin, M I Medvedev, K Iu Mukhin, M B Iskander, D A Kharlamov, N K Veselov
JournalZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 94 Issue 6 Pg. 28-33 ( 1994) ISSN: 1997-7298 [Print] Russia (Federation)
Vernacular TitleLechenie énkoratom infantil'nykh spazmov i sindroma Lennoksa--Gasto.
PMID7740870 (Publication Type: Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Anticonvulsants
  • encorat
  • Carbamazepine
  • Clonazepam
  • Ethosuximide
  • Valproic Acid
Topics
  • Anticonvulsants (adverse effects, therapeutic use)
  • Carbamazepine (therapeutic use)
  • Child, Preschool
  • Clonazepam (therapeutic use)
  • Drug Therapy, Combination
  • Epilepsy (diagnosis, drug therapy)
  • Ethosuximide (therapeutic use)
  • Female
  • Hemiplegia (diagnosis, drug therapy)
  • Humans
  • Infant
  • Male
  • Remission Induction
  • Spasms, Infantile (diagnosis, drug therapy)
  • Syndrome
  • Time Factors
  • Valproic Acid (adverse effects, analogs & derivatives, therapeutic use)

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