Role of oxytetracycline dihydrate in the treatment of mycoplasma-associated ovine keratoconjunctivitis in lambs.

Abstract

Thirty-six lambs were placed in two groups of 10 each, one group of 11 and one group of five. The first three groups were challenged with a field strain of Mycoplasma conjunctivae and the group of five lambs with an inactivated culture. One group of lambs was treated with oxytetracycline dihydrate as conjunctivitis developed at 1 day post-inoculation (dpi) and the other group was treated when the conjunctivitis was at its most severe (3 dpi). A rapid response to treatment was observed with a complete recovery obtained after 2 and 4 days, respectively. However, the treatment did not eliminate the M. conjunctivae infection. Conjunctivitis did not develop in the five lambs challenged with the inactivated culture.

• Authors: B D Hosie, A Greig
• Journal: The British veterinary journal (Br Vet J) 1995 Jan-Feb Vol. 151 Issue 1 Pg. 83-8 ISSN: 0007-1935 [Print] England
• PMID: 7735873 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Oxytetracycline

Topics

• Animals
• Keratoconjunctivitis, Infectious (drug therapy)
• Mycoplasma
• Mycoplasma Infections (drug therapy, veterinary)
• Oxytetracycline (therapeutic use)
• Sheep
• Sheep Diseases (drug therapy)