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[Efficacy of topical ciprofloxacin in the treatment of chronic otorrhea].

Abstract
The aim of the present study was to assess the clinical and bacteriological efficacy of ciprofloxacin in the treatment of chronic otitis media. Ciprofloxacin was randomly administered for ten days to two groups of patients. Group A was given 500 mg. orally twice a day. Group B received drops of ciprofloxacin in saline solution locally twice a day. We obtained a favorable clinical and bacteriological response. Bacteriological response observed in group B was statistically higher than that of group A (p < 0.01). Results obtained in this study suggest that ciprofloxacin locally administered is very effective in the treatment of chronic otitis media.
AuthorsV Povedano Rodríguez, M J Seco Piñero, A Jurado Ramos, P López Villarejo
JournalActa otorrinolaringologica espanola (Acta Otorrinolaringol Esp) 1995 Jan-Feb Vol. 46 Issue 1 Pg. 15-8 ISSN: 0001-6519 [Print] Spain
Vernacular TitleEficacia del ciprofloxacino tópico en el tratamiento de la otorrea crónica.
PMID7734157 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Ciprofloxacin
Topics
  • Administration, Oral
  • Administration, Topical
  • Adolescent
  • Adult
  • Aged
  • Bacteria (isolation & purification)
  • Chronic Disease
  • Ciprofloxacin (administration & dosage)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Otitis Media (drug therapy, microbiology)

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