Abstract |
The aim of the present study was to evaluate the influence of previous treatment on outcome and sensory disturbance after a retrogasserian glycerol injection for trigeminal neuralgia. Ninety-nine patients with trigeminal neuralgia underwent a retrogasserian glycerol rhizotomy. Fifty-three of those patients experienced recurrent pain after the previous treatment. At the 1 year follow-up, the outcome was excellent or good in 83% of patients with no previous treatment, compared with 60 and 75% in those patients with earlier glycerol injections or radiofrequency lesions, respectively. Quantitatively assessed, the sensory impairment was most pronounced in patients who had earlier radio-frequency lesions compared with patients not treated previously. The occurrence of dysesthesia was more frequent in patients who had been surgically treated earlier. A review of the literature showed that the concentration of the glycerol preparation used probably is of great importance in terms of pain relief and sensory sequelae.
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Authors | A T Bergenheim, M I Hariz |
Journal | Neurosurgery
(Neurosurgery)
Vol. 36
Issue 2
Pg. 303-9; discussion 309-10
(Feb 1995)
ISSN: 0148-396X [Print] United States |
PMID | 7731510
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Denervation
(methods)
- Female
- Glycerol
(therapeutic use)
- Humans
- Injections
- Male
- Middle Aged
- Pain Threshold
- Reoperation
- Sensory Thresholds
- Spinal Nerve Roots
(drug effects)
- Treatment Outcome
- Trigeminal Neuralgia
(physiopathology, surgery)
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