Delayed hypersensitivity to one low-molecular-weight heparin with tolerance of other low-molecular-weight heparins.

Abstract	We report a patient who developed infiltrated plaques at the sites of subcutaneous injection of a low-molecular-weight heparin. Skin tests and a lymphocyte transformation test revealed hypersensitivity to sandoparin and heparin sodium. The low-molecular-weight heparins nadroparin and dalteparin were subsequently tolerated without adverse effects. Possible risk factors for sensitization are discussed.
Authors	A J Bircher, P H Itin, D A Tsakiris, C Surber
Journal	The British journal of dermatology (Br J Dermatol) Vol. 132 Issue 3 Pg. 461-3 (Mar 1995) ISSN: 0007-0963 [Print] England
PMID	7718467 (Publication Type: Case Reports, Journal Article)
Chemical References	Heparin, Low-Molecular-Weight
Topics	Drug Hypersensitivity Drug Tolerance Female Heparin, Low-Molecular-Weight (adverse effects, immunology) Humans Hypersensitivity, Delayed (chemically induced) Lymphocyte Activation Middle Aged Skin Tests Varicose Ulcer (drug therapy)

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