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Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells.

Abstract
In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude mice. The tumours formed by the annexin VI+ A431 cells were morphologically and histologically similar to those formed by the wild-type cells.
AuthorsJ Theobald, A Hanby, K Patel, S E Moss
JournalBritish journal of cancer (Br J Cancer) Vol. 71 Issue 4 Pg. 786-8 (Apr 1995) ISSN: 0007-0920 [Print] England
PMID7710945 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Annexin A6
Topics
  • Animals
  • Annexin A6 (analysis, biosynthesis)
  • Carcinoma, Squamous Cell (metabolism, pathology)
  • Cell Line
  • Clone Cells
  • Humans
  • Immunohistochemistry
  • Mice
  • Mice, Nude
  • Transplantation, Heterologous
  • Tumor Cells, Cultured

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