Preoperative chemotherapy for mesoblastic nephroma.

Abstract

A neonate with extensive stage III mesoblastic nephroma was confirmed at operation to have a tumor that was too infiltrative and too advanced for primary excision. The abdomen was closed after multiple biopsies. Vincristine (1.1 mg/m2) was given intravenously once a week for a total of eight doses. Repeat CT scan confirmed shrinkage of the tumor and a nephrectomy could be performed safely and the tumor removed at the second laparotomy. CT scan repeated 1 year later showed no recurrence. This case illustrates the effective use of a single drug pre-excision chemotherapy which allowed a nephrectomy for extensive stage III mesoblastic nephroma to be carried out safely.

• Authors: K L Chan, K W Chan, C W Lee, H Saing
• Journal: Medical and pediatric oncology (Med Pediatr Oncol) Vol. 24 Issue 4 Pg. 271-3 (Apr 1995) ISSN: 0098-1532 [Print] United States
• PMID: 7700175 (Publication Type: Case Reports, Journal Article)

Topics

• Combined Modality Therapy
• Female
• Humans
• Infant, Newborn
• Kidney Neoplasms (congenital, drug therapy, surgery)
• Nephrectomy
• Nephroma, Mesoblastic (congenital, drug therapy, surgery)