Glycogen storage disease type Ib: infectious complications and measures for prevention.

Abstract	A patient with glycogen storage disease (GSD) type Ib, neutrophenia, chronic inflammatory bowel disease and recurrent abscesses was treated with recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF). GM-CSF (and also granulocyte colony stimulating factor) therapy markedly increased the neutrophil counts and reduced the frequency of infections and inflammation. We conclude that myeloid growth factors are effective for the treatment and prevention of acute infections and chronic inflammatory complications in patients with GSD Ib.
Authors	U Wendel, H Schroten, S Burdach, V Wahn
Journal	European journal of pediatrics (Eur J Pediatr) Vol. 152 Suppl 1 Pg. S49-51 ( 1993) ISSN: 0340-6199 [Print] Germany
PMID	7686491 (Publication Type: Case Reports, Journal Article)
Chemical References	Recombinant Proteins Granulocyte Colony-Stimulating Factor Granulocyte-Macrophage Colony-Stimulating Factor
Topics	Abscess (etiology, prevention & control) Adolescent Anus Diseases (etiology, prevention & control) Chronic Disease Female Glycogen Storage Disease Type I (complications) Granulocyte Colony-Stimulating Factor (therapeutic use) Granulocyte-Macrophage Colony-Stimulating Factor (therapeutic use) Humans Inflammatory Bowel Diseases (complications) Mouth Diseases (etiology, prevention & control) Neutropenia (etiology, prevention & control) Recombinant Proteins (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!