HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[The efficacy of cyclosporin in the treatment of myositis].

Abstract
Cyclosporin A (CyA) was used in 15 patients with corticosteroid-resistant myositis (11) and as a first-line drug (4). The criterion for improvement was recovery of strength. Additionally, changes in muscle enzyme values were evaluated. One patient left therapy because of gastric intolerance. Another patient, with severe pulmonary fibrosis, died 6 days after initiating therapy. In the other patients a favorable response was observed at approximately six weeks (range 3 weeks-3 months). Significant decreases in muscle enzyme values were observed. CyA was useful for treatment of corticosteroid-resistant patients. While it was efficient as a first line drug, the present report does not allow a comparative evaluation with corticosteroid therapy.
AuthorsJ Sánchez Román, M J Castillo Palma, C Ocaña Medina, I Wichmann, I Chinchón Lara, D I Segura Ayestarán
JournalRevista clinica espanola (Rev Clin Esp) Vol. 195 Issue 7 Pg. 449-54 (Jul 1995) ISSN: 0014-2565 [Print] Spain
Vernacular TitleEficacia de la ciclosporina en el tratamiento de las miositis.
PMID7667518 (Publication Type: Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Cyclosporine
Topics
  • Adult
  • Aged
  • Child
  • Chronic Disease
  • Cyclosporine (therapeutic use)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscles (drug effects, enzymology)
  • Myositis (classification, drug therapy, enzymology)
  • Remission Induction
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: