Basic analysis of dynamic study in cases of hepatocellular carcinoma using inversion recovery snap shot FLASH MR imaging with Gd-DTPA.

Abstract

Twenty patients with hepatocellular carcinoma were studied by dynamic sequential inversion recovery snap shot fast low angle shot (FLASH) imaging after the bolus injection of various amounts of Gd-DTPA. We determined the optimal dose of Gd-DTPA for depicting tumors as early marked enhancement and compared the method with dynamic CT by matching data acquisition time. The optimal dose was estimated to be 0.1 mmol/kg. Compared with dynamic CT, dynamic MRI showed rapid short-term enhancement in the early phase, while the contrast enhancement in the late phase lasted longer and was stronger than that of CT.

• Authors: Y Suto, M Kamba, T Kato, Y Ohta
• Journal: Radiation medicine (Radiat Med) 1995 Mar-Apr Vol. 13 Issue 2 Pg. 89-94 ISSN: 0288-2043 [Print] Japan
• PMID: 7667515 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Contrast Media
• Organometallic Compounds
• Pentetic Acid
• Gadolinium
• Gadolinium DTPA

Topics

• Aged
• Carcinoma, Hepatocellular (diagnosis, diagnostic imaging)
• Contrast Media
• Female
• Gadolinium (administration & dosage)
• Gadolinium DTPA
• Humans
• Liver Neoplasms (diagnosis, diagnostic imaging)
• Magnetic Resonance Imaging (methods)
• Male
• Middle Aged
• Organometallic Compounds (administration & dosage)
• Pentetic Acid (administration & dosage, analogs & derivatives)
• Predictive Value of Tests
• Tomography, X-Ray Computed