[The immune response in those ill with and convalescing from Q fever studied by using immunoenzyme analysis].

Abstract

The study of immune response in Q-fever patients and convalescents at different periods from the beginning of the disease demonstrated the diagnostic possibilities of the complement fixation test (CFT), the microagglutination test (MAT), the passive immunofluorescence test (PIFT) and the enzyme immunoassay (EIA). High effectiveness of EIA in comparison with CFT, MAT and PIFT was noted (97, 63, 87 and 91% respectively). The sensitivity of EIA was not less than 100-250 times higher than that of CFT, 15-100 times higher than that of MAT and 30-80 times higher than that of PIFT.

• Authors: E N Gorbachev, N K Tokarevich
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1995 May-Jun Issue 3 Pg. 99-102 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Izuchenie immunnogo otveta u bol'nykh i perebolevshikh Ku-likhoradkoĭ pri ispol'zovanii immunofermentnogo analiza.
• PMID: 7660714 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial

Topics

• Agglutination Tests
• Antibodies, Bacterial (blood)
• Complement Fixation Tests
• Convalescence
• Coxiella burnetii (immunology)
• Evaluation Studies as Topic
• Fluorescent Antibody Technique
• Humans
• Immunoenzyme Techniques (statistics & numerical data)
• Q Fever (immunology)
• Sensitivity and Specificity
• Time Factors