Abstract |
A total of 112 species of edible plants (122 samples) from Thailand were randomly collected, and their methanol extracts were screened for in vitro anti- tumor promoting activity using the inhibition test of Epstein-Barr virus (EBV) activation in Raji cells induced by 12-O-hexadecanoylphorbol-13-acetate (HPA, 40 ng/ml). It was found that 60% of these extracts inhibited EBV activation by 30% or more at a concentration of 200 mg/ml. Significantly, the ratio is markedly higher than that (26%) previously observed in common edible plants in Japan. Thus, physiological potentiality of edible Thai plants has been implied in terms of cancer chemoprevention.
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Authors | A Murakami, S Jiwajinda, K Koshimizu, H Ohigashi |
Journal | Cancer letters
(Cancer Lett)
Vol. 95
Issue 1-2
Pg. 139-46
(Aug 16 1995)
ISSN: 0304-3835 [Print] Ireland |
PMID | 7656222
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Anticarcinogenic Agents
(chemistry)
- Herpesvirus 4, Human
- Humans
- In Vitro Techniques
- Mutagenicity Tests
- Plants, Edible
(chemistry)
- Plants, Medicinal
(chemistry)
- Thailand
- Virus Replication
(drug effects)
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