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Treatment of Legionella pneumophila lung abscess with clindamycin.

Abstract
Clindamycin was used to successfully treat a lung abscess caused by Legionella pneumophila. The activity of clindamycin, erythromycin, and rifampin against cell-associated growth of L. pneumophila in human monocytes was determined by broth time-kill methodology. More killing of cell-associated growth of L. pneumophila was achieved with clindamycin than with erythromycin. Synergy with rifampin was demonstrated with both erythromycin and clindamycin.
AuthorsB P Buggy, L D Saravolatz
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis) Vol. 20 Issue 5 Pg. 1158-62 (May 1995) ISSN: 1058-4838 [Print] United States
PMID7619992 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Clindamycin
Topics
  • Adult
  • Clindamycin (therapeutic use)
  • Humans
  • Legionella pneumophila (drug effects)
  • Legionnaires' Disease (drug therapy)
  • Lung Abscess (drug therapy)
  • Male
  • Microbial Sensitivity Tests

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