| Abstract | A 26-year-old man was admitted to our hospital for evaluation of cavitary lesions on his chest X-ray film. Chest CT and conventional tomograms showed multiple cavities in both lung fields, as well as hilar and mediastinal lymphadenopathy. He had uveitis and the laboratory data showed a high level of angiotensin converting enzyme in the serum. Histological findings of the specimen obtained by transbronchial lung biopsy showed non-caseating epithelioid cell granuloma, consistent with sarcoidosis. Corticosteroid therapy (prednisolone 40 mg/day) resulted in reduction of the cavitary lesions and the lymphadenopathy. Negative bacteriological studies and the clinical course strongly suggested primary cavitation, a relatively rare form of pulmonary parenchymal involvement in sarcoidosis. |
| Authors | M Yamaguchi, K Ohta, H Takizawa, N Kobayashi, A Ishii, H Sugiyama, M Dohi, M Suko, K Ito, T Miyamoto
(Affiliation: Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Japan.)
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| Journal | Nihon Kyōbu Shikkan Gakkai zasshi
(Nihon Kyobu Shikkan Gakkai Zasshi)
Vol. 33
Issue 5
Pg. 533-7
(May 1995)
ISSN: 0301-1542 JAPAN |
| PMID | 7609339
(Publication Type: Case Reports, English Abstract, Journal Article)
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| Chemical References |
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| Topics |
- Adult
- Humans
- Lung
(radiography)
- Male
- Pneumothorax
(complications)
- Prednisolone
(administration & dosage)
- Sarcoidosis, Pulmonary
(complications, radiography)
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