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[A case of sarcoidosis with right pneumothorax and multiple cavities in both lung fields]

AbstractA 26-year-old man was admitted to our hospital for evaluation of cavitary lesions on his chest X-ray film. Chest CT and conventional tomograms showed multiple cavities in both lung fields, as well as hilar and mediastinal lymphadenopathy. He had uveitis and the laboratory data showed a high level of angiotensin converting enzyme in the serum. Histological findings of the specimen obtained by transbronchial lung biopsy showed non-caseating epithelioid cell granuloma, consistent with sarcoidosis. Corticosteroid therapy (prednisolone 40 mg/day) resulted in reduction of the cavitary lesions and the lymphadenopathy. Negative bacteriological studies and the clinical course strongly suggested primary cavitation, a relatively rare form of pulmonary parenchymal involvement in sarcoidosis.
AuthorsM Yamaguchi, K Ohta, H Takizawa, N Kobayashi, A Ishii, H Sugiyama, M Dohi, M Suko, K Ito, T Miyamoto (Affiliation: Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Japan.)
JournalNihon Kyōbu Shikkan Gakkai zasshi (Nihon Kyobu Shikkan Gakkai Zasshi) Vol. 33 Issue 5 Pg. 533-7 (May 1995) ISSN: 0301-1542 JAPAN
PMID7609339 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Prednisolone
Topics
  • Adult
  • Humans
  • Lung (radiography)
  • Male
  • Pneumothorax (complications)
  • Prednisolone (administration & dosage)
  • Sarcoidosis, Pulmonary (complications, radiography)