[Evaluation of nasal mucociliary clearance with a modified saccharin test].

Abstract

To measure the complex nasal clearance we propose to perform our variation of the Andersen saccharin method as a saccharin liquid test (SLT). The application of 3 molar aqueous sodium saccharin solutions with a Wiretrol capillary on the concha nasalis inferior or media allows simple handling, exact dosage, minimal nasal irritation and an increase in reproducibility. Application of 1 microlitre is sufficient to carry out the test. In the present study 48 healthy volunteers without any nose disease or history of sinusitis showed a saccharin transport rate of 10.4 (SD 4.2) minutes.

• Authors: E G Kleinschmidt, G Witt
• Journal: Laryngo- rhino- otologie (Laryngorhinootologie) Vol. 74 Issue 5 Pg. 286-8 (May 1995) ISSN: 0935-8943 [Print] Germany
• Vernacular Title: Zur Beurteilung der nasalen Mukoziliartätigkeit mit einem modifizierten Saccharintest.
• PMID: 7605567 (Publication Type: English Abstract, Journal Article)

Chemical References

• Saccharin

Topics

• Adolescent
• Adult
• Aged
• Ciliary Motility Disorders (diagnosis, physiopathology)
• Female
• Humans
• Male
• Middle Aged
• Mucociliary Clearance (physiology)
• Nasal Mucosa (physiopathology)
• Reference Values
• Reproducibility of Results
• Saccharin
• Smoking (adverse effects, physiopathology)