[Cerebrolysin in the treatment of partial optic atrophy in children].

Abstract

The purpose of the trial was to investigate efficacy of cerebrolysin in children with partial optic atrophy and to compare different ways of injections of the drug. Cerebrolysin was injected in retrobulbar space and in Tenon's space. The drug was given separately and in combination with trental. Favorable effect has been achieved in all the patients treated with cerebrolysin injections in Tenon's space. In patients treated with retrobulbar injections of cerebrolysin and with injections of cerebrolysin and trental improvement occurred in 50% of cases. In control group, who did not receive cerebrolysin favorable results were achieved in 25% of patients. A 12-month follow-up study stated stability of the effect of cerebrolysin.

• Authors: E I Sidorenko, M R Guseva, L A Dubovskaia, I V Lobanova
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 95 Issue 3 Pg. 51-4 ( 1995) ISSN: 1997-7298 [Print] Russia (Federation)
• Vernacular Title: Tserebrolizin v lechenii chastichnykh atrofiĭ zritel'nogo nerva u deteĭ.
• PMID: 7571926 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)

Chemical References

• Amino Acids
• cerebrolysin

Topics

• Amino Acids (administration & dosage)
• Child
• Drug Therapy, Combination
• Eye
• Humans
• Injections, Intralesional
• Injections, Intramuscular
• Optic Atrophy (drug therapy, physiopathology)
• Sclera
• Therapeutic Irrigation (methods)
• Visual Acuity (drug effects)