Role of technetium-99m pertechnetate scintigraphy in the management of extra-abdominal fibromatosis.

Abstract

The purpose of this study was to investigate technetium-99m pertechnetate (Tc-99m) as a tumor-scanning agent in patients with extra-abdominal fibromatosis, and to establish the sensitivity of this type of scintigraphy. Eleven patients with extra-abdominal fibromatosis were studied: all but one having postsurgical recurrences. Of the 11 patients, diagnosed histologically, 5 underwent repeated Tc-99m scintigraphic follow-up examinations. The injected 370 MBq Tc-99m gave us an early scintigram within 10 min and a delayed one 2 h later. For adequate comparison, the region of interest (ROI) of the scintigram was placed over the tumor. The tumor-to-background (T/BG) count ratio was computed. Extra-abdominal fibromatoses, even recurrences, were demonstrated scintigraphically in both the early and the delayed phase, in all 11 patients. The average T/BG ratio was 2.11 in the early scintigram and 2.15 in the delayed one. The sensitivity and the specificity were both 100%. Tc-99m scintigraphy has proved useful in detecting extra-abdominal fibromatoses and in the follow-up of patients.

• Authors: S Terui, T Terauchi, H Abe, Y Muramatsu, H Fukuma, Y Beppu, R Yokoyama
• Journal: Skeletal radiology (Skeletal Radiol) Vol. 24 Issue 5 Pg. 331-6 (Jul 1995) ISSN: 0364-2348 [Print] Germany
• PMID: 7570152 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Sodium Pertechnetate Tc 99m

Topics

• Adult
• Female
• Fibroma (diagnostic imaging, pathology)
• Follow-Up Studies
• Humans
• Magnetic Resonance Imaging
• Male
• Neoplasm Recurrence, Local (diagnostic imaging, pathology)
• Predictive Value of Tests
• Radionuclide Imaging
• Sensitivity and Specificity
• Sodium Pertechnetate Tc 99m
• Soft Tissue Neoplasms (diagnostic imaging, pathology)