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[Double cancer in patients with adult T cell leukemia].

Abstract
We have studied the incidence and characteristics of associated neoplasms in 210 ATL patients. Twelve patients had other primary neoplasms and the incidence of double cancer was 5.7%. The additional malignancies in ATL patients consisted of 4 cases of stomach, 3 cases of colon and one of each lung, ovary, uterus, liver and bladder cancer. In metachronous double cancer patients, the neoplasm was found before the time of diagnosis of ATL in 5 out of 6 patients. Immunodeficiency due to HTLV-I infection as well as chemotherapy for the preceding neoplasm are suggested to be related to the leukemogenesis of ATL.
AuthorsT Makino, A Utsunomiya, S Suzuki, K Ishizuka, K Nakahara, T Takeshita, N Daino, Y Chuma, M Otsuka, K Uozumi
Journal[Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 36 Issue 8 Pg. 792-4 (Aug 1995) ISSN: 0485-1439 [Print] Japan
PMID7563615 (Publication Type: English Abstract, Journal Article)
Topics
  • Aged
  • Aged, 80 and over
  • Colonic Neoplasms (pathology)
  • Female
  • Humans
  • Leukemia, T-Cell (pathology)
  • Male
  • Middle Aged
  • Neoplasms, Second Primary
  • Stomach Neoplasms (pathology)

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