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Trisomy 14: a recurring cytogenetic abnormality associated with myeloid disorders.

Abstract
Trisomy 14 as single karyotype aberration was detected in three patients, two with acute myeloblastic leukemia, AML-M2 type, and one with aplastic anemia. These new observations and the 28 previously reported cases confirm that trisomy 14 is a primary non random change, mostly confined to myeloid disorders.
AuthorsH Poirel, P Jonveaux, M T Daniel, R Berger
JournalLeukemia & lymphoma (Leuk Lymphoma) Vol. 17 Issue 5-6 Pg. 455-7 (May 1995) ISSN: 1042-8194 [Print] United States
PMID7549837 (Publication Type: Case Reports, Journal Article)
Topics
  • Adult
  • Aged
  • Anemia, Aplastic (diagnosis, genetics, therapy)
  • Bone Marrow Diseases (genetics)
  • Chromosomes, Human, Pair 14
  • Fatal Outcome
  • Female
  • Humans
  • Karyotyping
  • Leukemia, Myeloid, Acute (diagnosis, genetics, therapy)
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes (genetics)
  • Trisomy

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