[Laboratory control of effectiveness of chemotherapy in melioidosis].

An undoubtable role of the melioidosis germ persistence in the form of L-variants with the development of DTH in the relapses of the disease was stated. Serological reactions such as CFT and PHAR were shown to be of the diagnostic value but it was by far lower than the allergotest. No correlation between the antibody titers in the tested sera and the isolation of the bacterial or L-variants of the melioidosis germ was observed. The criteria of the recovery from melioidosis were: stable normalization of the patient temperature, positive time course of the body weight changes, negative tests for the type and morphologically changed forms of the melioidosis germ and no allergic reactions.
AuthorsV P Batmanov, V I Iliukhin, Iu V Antonov
JournalAntibiotiki i khimioterapii︠a︡ = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoĭ i mikrobiologicheskoĭ promyshlennosti SSSR (Antibiot Khimioter) Vol. 40 Issue 2 Pg. 41-5 (Feb 1995) ISSN: 0235-2990 [Print] RUSSIA
Vernacular TitleLaboratornyĭ kontrol' éffektivnosti khimioterapii pri melioidoze.
PMID7541620 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Complement System Proteins
  • Sulfamethoxazole
  • Animals
  • Anti-Bacterial Agents
  • Burkholderia pseudomallei (isolation & purification)
  • Complement System Proteins (metabolism)
  • Drug Hypersensitivity
  • Drug Therapy, Combination (therapeutic use)
  • Guinea Pigs
  • Hypersensitivity, Delayed
  • Laboratories
  • Melioidosis (drug therapy, microbiology)
  • Quality Assurance, Health Care
  • Serologic Tests
  • Sulfamethoxazole (therapeutic use)
  • Titrimetry
  • Trimethoprim, Sulfamethoxazole Drug Combination (therapeutic use)

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