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Flare of arthritis with successful treatment of Felty's syndrome with granulocyte colony stimulating factor (GCSF).

AbstractA 58-year-old white male with Felty's syndrome was successfully treated with granulocyte colony stimulating factor (GCSF). GCSF can correct the granulocytopenia of Felty's syndrome and may be a beneficial therapeutic adjunct in patients who have serious infections associated with neutropenia. The patient developed a flare of arthritis concomitant with increased circulating neutrophils following GCSF therapy.
AuthorsS Q Hayat, M Hearth-Holmes, R E Wolf (Affiliation: Section of Rheumatology, Louisiana State University Medical Center, Shreveport 71130, USA.)
JournalClinical rheumatology (Clin Rheumatol) Vol. 14 Issue 2 Pg. 211-2 (Mar 1995) ISSN: 0770-3198 BELGIUM
PMID7540528 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Recombinant Proteins
  • Granulocyte Colony-Stimulating Factor
Topics
  • Agranulocytosis (drug therapy, etiology)
  • Arthritis, Rheumatoid (complications, physiopathology)
  • Felty's Syndrome (complications, drug therapy, physiopathology)
  • Granulocyte Colony-Stimulating Factor (adverse effects, therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Recombinant Proteins (therapeutic use)