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Prevalence of markers of hepatitis B virus infection among the general population of the municipality of Slavonski Brod.

Abstract
To assess the prevalence of hepatitis B viral infection in general population of the Community of Slavonski Brod, sera from 2,142 apparently healthy individuals were tested for the hepatitis B virus (HBV) markers: surface antigen and antibody (HBsAg and anti-HBs), and core antibody (anti-HBc), by radio and enzyme-immunoassay. The HBsAg results showed a general prevalence of 1.8%(38/2,142): for males 1.9% and for females 1.6%. The highest HBsAg incidence rates (2.1% and 1.9%) were found in young adults aged 21-30, respective in older children and adolescents, from 11 to 20 years. The lowest HBsAg prevalence (1.0%) was proved in children from 1 to 5 years, while in sera of 68 examined sucklings HBsAg was not detected. The HBsAg incidence was 1.9% (21/1132) in urban and 1.7% (17/1010) in rural inhabitants. The overall prevalence rate of total HBV infection in 13.7% (294/2,142) examinees was found. There was no difference in the prevalence of HBV infection in males 15.7% (177/1130) and females 11.6% (117/1012), as well as in persons living in rural 12.5% (126/1010) or in urban 14.8% (168/1132) areas. The prevalence rate of anti-HBs and anti-HBc gradually increased with increasing age, starting at about 3.2% in the youngest, and reaching 15.5% in adults over 50 years. The results obtained have place the Community of Slavonski Brod among areas with an intermediate endemicity of HBV infection.
AuthorsO Jelić, D Jelić, I Balen, A Jelić, N Jelić, I Mihaljević
JournalActa medica Croatica : casopis Hravatske akademije medicinskih znanosti (Acta Med Croatica) Vol. 48 Issue 3 Pg. 111-6 ( 1994) ISSN: 1330-0164 [Print] Croatia
PMID7532046 (Publication Type: Journal Article)
Chemical References
  • Hepatitis B Antibodies
  • Hepatitis B Surface Antigens
Topics
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Croatia (epidemiology)
  • Female
  • Hepatitis B (epidemiology)
  • Hepatitis B Antibodies (analysis)
  • Hepatitis B Surface Antigens (analysis)
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Prevalence
  • Seroepidemiologic Studies

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