Abstract |
Cardioplegic myocardial protection with magnesium asparaginate procaine ( Cardioplegin) is assessed in normothermic ischemia by left ventricular function curves. Different ischemic times (20, 30, 40, and 50 min) and different doses of Cardioplegin (2, 4, and 6 ml/kg) were studied in 68 mongrel dogs. Postischemic myocardial function was depressed in all experiments. However, in the Cardioplegin groups all animals showed signs of recovery and a significant, but not dose-related, hemodynamic improvement compared to the controls.
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Authors | B Walpoth, M Fornaro, W von Gossler, M Turina |
Journal | Chirurgisches Forum fur experimentelle und klinische Forschung
(Chir Forum Exp Klin Forsch)
Issue 1978
Pg. 99-102
( 1978)
ISSN: 0303-6227 [Print] Germany |
Vernacular Title | Tierexperimentelle Beurteilung des Myokardschutzes mittels Magnesium-asparaginat-procain-Lösung. |
PMID | 752612
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Drug Combinations
- Procaine
- Sorbitol
- Asparagine
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Topics |
- Animals
- Asparagine
(administration & dosage, pharmacology)
- Dogs
- Drug Combinations
- Heart
(drug effects)
- Heart Arrest, Induced
- Ischemia
(prevention & control)
- Procaine
(administration & dosage, pharmacology)
- Sorbitol
(administration & dosage, pharmacology)
- Time Factors
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