Abstract |
A single poroid neoplasm composed of three histologically distinct lesions (hidroacanthomas simplex, eccrine poroma, and dermal duct tumor) is reported. Comparative histologic, histochemical, and electron-microscopic studies revealed that each tumor subtype contained varying proportions of poroid cells, clear cells, and cuticular cells. The major component of all three neoplasms was poroid cells, which, under the electron microscope, were characterized by a few, small, poorly developed desmosomes, and were histochemically characterized by a positive succinic dehydrogenase reaction. The dermal duct tumor was cultured, and showed similar histochemical findings to the in vivo poroid cells. These results suggest that poroid cells play the most important role in the histogenesis of these three neoplasms.
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Authors | H Kakinuma, R Miyamoto, U Iwasawa, S Baba, H Suzuki |
Journal | The American Journal of dermatopathology
(Am J Dermatopathol)
Vol. 16
Issue 1
Pg. 66-72
(Feb 1994)
ISSN: 0193-1091 [Print] United States |
PMID | 7512801
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Acrospiroma
(chemistry, pathology, ultrastructure)
- Aged
- Cytoplasm
(ultrastructure)
- Cytoplasmic Granules
(ultrastructure)
- Epidermis
(pathology)
- Glycogen
(analysis)
- Humans
- Keratins
(analysis)
- Male
- Microscopy, Electron
- Neoplasms, Glandular and Epithelial
(chemistry, pathology, ultrastructure)
- Neoplasms, Multiple Primary
(chemistry, pathology, ultrastructure)
- Skin Neoplasms
(chemistry, pathology, ultrastructure)
- Sweat Gland Neoplasms
(chemistry, pathology, ultrastructure)
- Tumor Cells, Cultured
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