Plasmapheresis maintained renal function in an allograft with recurrent membranoproliferative glomerulonephritis type I.

Abstract

Six months posttransplant, a 38-year-old woman developed acute renal failure due to recurrent idiopathic membranoproliferative glomerulonephritis (MPGN) type I. MPGN was associated with an elevated rheumatoid factor and IgM deposition in the mesangium. Plasmapheresis with albumin replacement improved and maintained renal function for over a year while cytotoxic agents were administered in an attempt to control the glomerulonephritis. The patient currently has a functional renal allograft 2 years posttransplant.

• Authors: K A Muczynski
• Journal: American journal of nephrology (Am J Nephrol) Vol. 15 Issue 5 Pg. 446-9 ( 1995) ISSN: 0250-8095 [Print] Switzerland
• PMID: 7503148 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Immunoglobulin M
• Rheumatoid Factor

Topics

• Adult
• Female
• Glomerulonephritis, Membranoproliferative (physiopathology, surgery, therapy)
• Humans
• Immunoglobulin M (blood)
• Kidney (physiopathology)
• Kidney Transplantation
• Plasmapheresis
• Recurrence
• Rheumatoid Factor (blood)