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The cost effectiveness of azithromycin for Chlamydia trachomatis infections in women.

AbstractBACKGROUND AND OBJECTIVES:
Azithromycin, an approved single-dose therapy for cervical chlamydia infections, costs four times as much as doxycycline, the standard multidose theapy.
GOAL OF THIS STUDY:
This study examined whether azithromycin is cost effective for treating cervical chlamydia infections.
STUDY DESIGN:
Two diagnostic strategies were compared: 1) laboratory confirmation of chlamydia, and 2) presumptive diagnosis from the perspective of the healthcare system and the publicly funded clinic.
RESULTS:
From the healthcare perspective, the cost per case of pelvic inflammatory disease prevented with azithromycin ranges from a savings of $3,502 for laboratory confirmation to a cost of $792 for presumptive diagnosis. From the publicly funded clinic perspective, the cost per case of pelvic inflammatory disease prevented ranges from $709 for lab-confirmed diagnosis to $3,969 for presumptive treatment.
CONCLUSION:
For the healthcare system, azithromycin is a cost-effective alternative to doxycycline. However, the cost of azithromycin must decrease markedly for it to be less costly to the publicly funded clinic.
AuthorsA C Haddix, S D Hillis, W J Kassler
JournalSexually transmitted diseases (Sex Transm Dis) 1995 Sep-Oct Vol. 22 Issue 5 Pg. 274-80 ISSN: 0148-5717 [Print] United States
PMID7502180 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Azithromycin
Topics
  • Anti-Bacterial Agents (economics, therapeutic use)
  • Azithromycin (economics, therapeutic use)
  • Chlamydia Infections (complications, drug therapy, economics)
  • Chlamydia trachomatis
  • Cohort Studies
  • Cost-Benefit Analysis
  • Female
  • Humans
  • Pelvic Inflammatory Disease (economics, etiology, prevention & control)

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