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alpha-Linolenic acid: a preventive in secondary coronary events?

Abstract
In a 5-year study of survivors of a first myocardial infarction, the effect of an alpha-linolenic acid-enriched diet (experimental) was compared with the prudent diet of the American Heart Association (control) in prevention of secondary coronary events. After a mean follow-up of 27 months, there were 5 nonfatal myocardial infarctions and 3 cardiac deaths in the experimental group versus 17 nonfatal myocardial infarctions and 16 cardiac deaths in the control group. Overall mortality was 20 in the control and 8 in the experimental group. An alpha-linolenic acid-enriched diet appears to be effective in secondary prevention of coronary events, but a follow-up trial with a larger sample size is suggested.
AuthorsI S Hartman
JournalNutrition reviews (Nutr Rev) Vol. 53 Issue 7 Pg. 194-7 (Jul 1995) ISSN: 0029-6643 [Print] United States
PMID7494621 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Review)
Chemical References
  • alpha-Linolenic Acid
Topics
  • American Heart Association
  • Clinical Trials as Topic
  • Diet
  • Follow-Up Studies
  • Humans
  • Myocardial Infarction (mortality, prevention & control)
  • Randomized Controlled Trials as Topic
  • United States
  • alpha-Linolenic Acid (administration & dosage, standards, therapeutic use)

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