Second primary malignancies in the head and neck cancer patient.

Abstract

With improvements in locoregional control, the problem of second primary malignancies is rapidly being pushed to the forefront of head and neck oncology. While the constant long-term risk for the head and neck cancer patient has been well established, efforts at prevention, early detection, and treatment have been somewhat futile. Recent advances in genetic predisposition, biomarkers, photodiagnostic imaging, and differentiation therapy may soon offer improved outcomes. The literature is reviewed and current research is presented regarding the history, epidemiology, etiology, diagnosis, and treatment of second primary malignancies.

• Authors: E M Sturgis, R H Miller
• Journal: The Annals of otology, rhinology, and laryngology (Ann Otol Rhinol Laryngol) Vol. 104 Issue 12 Pg. 946-54 (Dec 1995) ISSN: 0003-4894 [Print] United States
• PMID: 7492066 (Publication Type: Journal Article, Review)

Topics

• Carcinoma, Squamous Cell
• Head and Neck Neoplasms
• Humans
• Neoplasms, Multiple Primary
• Neoplasms, Second Primary
• Risk Factors