HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The benefits of estrogen replacement therapy on oral health. The Leisure World cohort.

AbstractBACKGROUND:
Several studies have demonstrated a relationship between tooth loss and alveolar residual ridge resorption and systemic osteoporosis. The recognized benefit of estrogen replacement therapy (ERT) in postmenopausal osteoporosis prompted review of the Leisure World Cohort Study regarding the effects of ERT on tooth loss and the need for dentures in older women.
METHODS:
The Leisure World Cohort, established in 1981, comprises 13,979 residents (8877 women) of a retirement community. Of the 5935 cohort women alive in 1992, 3921 returned a dental survey with sufficient information to analyze relationships with ERT as reported on the original baseline questionnaire.
RESULTS:
After adjusting for age, tooth loss and rates of edentia were significantly lower in estrogen users than in nonusers (relative risk for edentia, 0.64; 95% confidence interval, 0.51 to 0.79). The proportion of women with edentia decreased with increasing duration of ERT. Denture wearing was also less common in estrogen users than in nonusers (relative risk, 0.81; 95% confidence interval, 0.71 to 0.93) and decreased with increasing duration of ERT.
CONCLUSION:
Estrogen replacement therapy may be beneficial in preventing tooth loss and the need for dentures in older women.
AuthorsA Paganini-Hill
JournalArchives of internal medicine (Arch Intern Med) Vol. 155 Issue 21 Pg. 2325-9 (Nov 27 1995) ISSN: 0003-9926 [Print] United States
PMID7487257 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Topics
  • Aged
  • Aged, 80 and over
  • Alveolar Bone Loss (etiology, prevention & control)
  • Cohort Studies
  • Confidence Intervals
  • Dental Health Surveys
  • Dentures
  • Estrogen Replacement Therapy
  • Female
  • Humans
  • Middle Aged
  • Oral Health
  • Risk
  • Surveys and Questionnaires
  • Tooth Loss (etiology, prevention & control)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: