Human immunodeficiency virus rather than hepatitis C virus infection is relevant to the development of an anti-cardiolipin antibody.

Abstract

We have investigated whether or not a relationship exists between anti-cardiolipin antibody (aCL) positivity and human immunodeficiency virus type 1 (HIV) and/or hepatitis C virus (HCV), and we have attempted to clarify which virus has close association with the development of aCL. We found that aCL positivity in HIV-infected patients was significantly higher than in HCV-infected patients. Furthermore, HIV/HCV dual-infected patients exhibited a higher aCL positivity than patients infected by HCV alone. From these results, we conclude that HIV rather than HCV plays an important role in the development of aCL.

• Authors: M Gotoh, J Matsuda
• Journal: American journal of hematology (Am J Hematol) Vol. 50 Issue 3 Pg. 220-2 (Nov 1995) ISSN: 0361-8609 [Print] United States
• PMID: 7485085 (Publication Type: Journal Article)

Chemical References

• Antibodies, Anticardiolipin

Topics

• Antibodies, Anticardiolipin (metabolism)
• HIV Infections (immunology)
• Hemophilia A (complications)
• Hepatitis C (immunology)
• Humans