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[Dermatomyositis: successful therapy with high dosage intravenous 7S immunoglobulins].

Abstract
This report describes the successful administration of high dose, intravenous 7S immunoglobulins (IG) to an 11 year-old girl with corticosteroid-resistant dermatomyositis. Clinical symptoms improved immediately and the pathological laboratory findings normalized within 10 days of commencement of immunoglobulin therapy. After three cycles of IG the patient showed complete remission of the muscular and dermatological findings. On follow-up examination after one year the patient remained symptom-free in the absence of any therapy and was leading a normally active life. The efficacy of IG therapy in this case is reviewed in the light of the literature.
AuthorsU Zifko, W Grisold
JournalWiener klinische Wochenschrift (Wien Klin Wochenschr) Vol. 107 Issue 17 Pg. 522-4 ( 1995) ISSN: 0043-5325 [Print] Austria
Vernacular TitleDermatomyositis: Erfolgreiche Therapie mit hochdosierten intravenös applizierten 7S-Immunoglobulinen.
PMID7483635 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Prednisolone
Topics
  • Child
  • Dermatomyositis (immunology, therapy)
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Immunization, Passive
  • Prednisolone (administration & dosage, adverse effects)

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