[Relapsing infections associated with high serum IgE levels Buckley's syndrome (author's transl)].

Abstract

An 8-year old girl suffering from chronic relapsing staphylococcal skin infection since the first days of life was found to have extremely high (up to 26,500 units/ml) serum IgE levels and impaired polymorphonuclear chemotaxis. The other immunological tests appeared to be normal. There seemed to be a correlation between impaired chemotaxis and rise in IgE, the latter perhaps being related to a deficiency in some thymus-dependent lymphocyte functions.

• Authors: M L Perraudin, M Larregue, P H Trung, J C Desbois, A Herrault
• Journal: La Nouvelle presse medicale (Nouv Presse Med) Vol. 9 Issue 22 Pg. 1571-5 (May 17 1980) ISSN: 0301-1518 [Print] France
• Vernacular Title: Infections récidivantes avec hypergammaglobulinémie E. Syndrome de Buckley.
• PMID: 7465328 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Immunoglobulins
• Immunoglobulin E

Topics

• Chemotaxis, Leukocyte
• Child
• Chronic Disease
• Female
• Humans
• Hypergammaglobulinemia (complications, immunology)
• Immunoglobulin E (metabolism)
• Immunoglobulins (analysis)
• Lymphocyte Activation
• Lymphocytes (immunology)
• Rosette Formation
• Skin Diseases, Infectious (complications, immunology)
• Staphylococcal Infections (complications, immunology)