[Parasympathicolytic treatment of abnormal neurogenic bladder function: a urodynamic study (author's transl)].

Abstract

The effect of two parasympatholytic drugs, trospium chloride and hyoscine-N-butylbromide, was studied by urodynamic tests in 20 patients with spastic neurogenic bladder function. After intravenous injection of 0.6 mg trospium chloride or 60 mg hyoscine-N-butyl bromide bladder capacity increased significantly, while the degree of spasm and the response in the ice water test decreased significantly. Maximal sphincter pressure, resting bladder pressure, maximal bladder filling pressure and abdominal pressure remained unchanged.

• Authors: A Wolters, J Sökeland, W Weil, H Kopf
• Journal: Deutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 105 Issue 39 Pg. 1344-7 (Sep 26 1980) ISSN: 0012-0472 [Print] Germany
• Vernacular Title: Parasympathikolytische Therapie neurogener Blasenfunktionsstörungen. Urodynamische Untersuchungen.
• PMID: 7460781 (Publication Type: English Abstract, Journal Article)

Chemical References

• Benzilates
• Nortropanes
• Parasympatholytics
• Pyrrolidines
• trospium chloride
• Butylscopolammonium Bromide

Topics

• Benzilates
• Butylscopolammonium Bromide (therapeutic use)
• Humans
• Male
• Manometry
• Nortropanes (therapeutic use)
• Parasympatholytics (therapeutic use)
• Pyrrolidines (therapeutic use)
• Urinary Bladder, Neurogenic (drug therapy)
• Urodynamics