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Studies on the mechanism of experimental porphyria and ferrochelatase inhibition produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine.

AuthorsT R Tephly, A H Gibbs, G Ingall, F De Matteis
JournalThe International journal of biochemistry (Int J Biochem) Vol. 12 Issue 5-6 Pg. 993-8 ( 1980) ISSN: 0020-711X [Print] England
PMID7450161 (Publication Type: Journal Article)
Chemical References
  • Pyridines
  • Dicarbethoxydihydrocollidine
  • Lyases
  • Ferrochelatase
Topics
  • Animals
  • Dicarbethoxydihydrocollidine (pharmacology)
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • Ferrochelatase (antagonists & inhibitors)
  • Liver (drug effects, enzymology)
  • Lyases (antagonists & inhibitors)
  • Male
  • Mice
  • Microsomes, Liver (enzymology)
  • Mitochondria, Liver (enzymology)
  • Porphyrias (chemically induced, enzymology)
  • Pyridines (pharmacology)
  • Rats
  • Species Specificity

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