[Histological and ultrastructural studies on liver of rats treated with tiadenol].

Abstract

By hystological and electronmicroscopical study liver of rats treated with tiadenol at a daily dose of 100 and 200 mg for 30 days, we could demonstrate: lack of necrosis and interstitial phlogosis and, especially in those animals treated with greater doses, numerical increase of peroxisomes, hypertrophy of SER and RER and a lesser regularity of glycogen distribution.

• Authors: O Ciraolo, G Carrozza, L Petrelli, C Scuderi, S Giarrizzo, V Nicita Mauro, D Ceruso
• Journal: Bollettino della Societa italiana di biologia sperimentale (Boll Soc Ital Biol Sper) Vol. 56 Issue 11 Pg. 1157-63 (Jun 15 1980) ISSN: 0037-8771 [Print] Italy
• Vernacular Title: Ricerche istologiche ed ultrastrutturali sul fegato di ratti trattati con tiadenolo.
• PMID: 7448023 (Publication Type: English Abstract, Journal Article)

Chemical References

• Fatty Alcohols
• Liver Glycogen
• tiadenol

Topics

• Animals
• Dose-Response Relationship, Drug
• Endoplasmic Reticulum (ultrastructure)
• Fatty Alcohols (pharmacology)
• Female
• Histocytochemistry
• Liver (drug effects, metabolism, ultrastructure)
• Liver Glycogen (metabolism)
• Male
• Microbodies (ultrastructure)
• Microscopy, Electron
• Rats