Intrauterine irrigation with cefamandole nafate solution at cesarean section: a preliminary report.

Abstract

The effectiveness of intrauterine irrigation with an antibiotic solution of cefamandole nafate in reducing the incidence of endometritis after cesarean section was studied in a prospective, double-blind fashion. Ninety patients who underwent cesarean section at Tripler Army Medical Center were divided into three equal groups. Each group received one of the following treatments at the time of operation: (1) intrauterine irrigation with the antibiotic solution, (2) irrigation with normal saline solution, or (3) no irrigation. The resulting incidences of endometritis were 0%, 26.7%, and 23.3%, respectively. Intrauterine irrigation with cefamandole nafate solution at the time of cesarean section significantly reduced the incidence of endometritis.

• Authors: W H Long, E G Rudd, M B Dillon
• Journal: American journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 138 Issue 7 Pt 1 Pg. 755-8 (Dec 01 1980) ISSN: 0002-9378 [Print] United States
• PMID: 7446607 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Cephalosporins
• Sodium Chloride
• Cefamandole
• cefamandole nafate

Topics

• Cefamandole (administration & dosage, analogs & derivatives)
• Cephalosporins (administration & dosage)
• Cesarean Section
• Double-Blind Method
• Endometritis (prevention & control)
• Female
• Humans
• Postoperative Complications (prevention & control)
• Pregnancy
• Prospective Studies
• Risk
• Sodium Chloride (administration & dosage)
• Therapeutic Irrigation