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Clinical study of detorubicin. EORTC Clinical Screening Group.

Abstract
A phase II trial of detorubicin (DTR) has been conducted on 164 patients with solid tumors. Regressions greater than or equal to 50% were obtained in 23% of the breast carcinoma patients, in 17% of the head and neck carcinoma patients and melanoma patients, and in 6% of the uteri cervix carcinoma patients. DTR seems to be as toxic as adriamycin for bone marrow and heart, but might induce a little less alopecia.
Authors
JournalRecent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer (Recent Results Cancer Res) Vol. 74 Pg. 184-91 ( 1980) ISSN: 0080-0015 [Print] Germany
PMID7444139 (Publication Type: Journal Article)
Chemical References
  • Antibiotics, Antineoplastic
  • detorubicin
  • Daunorubicin
Topics
  • Antibiotics, Antineoplastic (adverse effects, therapeutic use)
  • Daunorubicin (adverse effects, analogs & derivatives, therapeutic use)
  • Drug Evaluation
  • Humans
  • Neoplasms (drug therapy)

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