Abstract |
A phase II trial of detorubicin (DTR) has been conducted on 164 patients with solid tumors. Regressions greater than or equal to 50% were obtained in 23% of the breast carcinoma patients, in 17% of the head and neck carcinoma patients and melanoma patients, and in 6% of the uteri cervix carcinoma patients. DTR seems to be as toxic as adriamycin for bone marrow and heart, but might induce a little less alopecia.
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Authors | |
Journal | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
(Recent Results Cancer Res)
Vol. 74
Pg. 184-91
( 1980)
ISSN: 0080-0015 [Print] Germany |
PMID | 7444139
(Publication Type: Journal Article)
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Chemical References |
- Antibiotics, Antineoplastic
- detorubicin
- Daunorubicin
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Topics |
- Antibiotics, Antineoplastic
(adverse effects, therapeutic use)
- Daunorubicin
(adverse effects, analogs & derivatives, therapeutic use)
- Drug Evaluation
- Humans
- Neoplasms
(drug therapy)
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