[The effect of Urografin on sensorineural deafness. A clinical study (author's transl)].

Abstract

Prof. Morimitsu (Fukuoka, Japan) reported a case of hearing improvement after the intravenous administration of Urografin in 1976. Because we had a similar case, injected 10 ml of Urografin (76%) intravenously in 130 patients with sensorineural deafness and tinnitus, which had not improved with previous treatment consisting of vasodilators and stellate ganglion blocks. 21 patients had a hearing improvement after Urografin-therapy; the tinnitus disappeared in 8 cases, and 2 patients noticed an improvement of their hearing and tinnitus. No adverse reactions to these injections, except for one case with a mild cutaneous allergy, were observed. The data did not reveal any particular clinical or audiological criteria which indicated a favourable prognosis with Urografin-therapy.

• Authors: M Strohm
• Journal: Laryngologie, Rhinologie, Otologie (Laryngol Rhinol Otol (Stuttg)) Vol. 59 Issue 3 Pg. 159-62 (Mar 1980) ISSN: 0340-1588 [Print] Germany
• Vernacular Title: Erfahrungen mit der Gabe von Urografin bei Innenohrschwerhörigkeit.
• PMID: 7442398 (Publication Type: English Abstract, Journal Article)

Chemical References

• Diatrizoate
• Diatrizoate Meglumine

Topics

• Deafness (drug therapy)
• Diatrizoate (analogs & derivatives)
• Diatrizoate Meglumine (adverse effects, therapeutic use)
• Female
• Humans
• Injections, Intravenous
• Male
• Tinnitus (drug therapy)